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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Mucosal Immunol. 2012 Sep 12;6(2):393–404. doi: 10.1038/mi.2012.83

Figure 3. E7-specific and total CD8 T-cells in CV of E7 immunized Trif KO, Cardif KO and Trif-Cardif double KO mice, ivag challenged with CpG of PIC.

Figure 3

Groups of Trif KO (left panels), Cardif KO (middle panels) and Trif-Cardif double KO (right panels) mice were s.c. immunized with the adjuvanted E7 vaccine and 5 days later ivag instilled with PBS, PIC or CpG. Mice were sacrificed three days later and cells recovered from individual CV were stained with CD8-APC antibodies and TetE749-57-PE or TetL1165-173-PE (as control). The percentages of TetE7+ CD8+ cells (A) and total CD8+ cells are indicated (B). The horizontal bars represent the mean percentages. Significant differences are indicated by * p< 0.05, ** p< 0.01, *** p< 0.001.