Skip to main content
. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Mucosal Immunol. 2012 Sep 12;6(2):393–404. doi: 10.1038/mi.2012.83

Figure 5. Expression of chemokine receptors and integrin/selectin ligands in the T-cells from CV upon ivag CpG.

Figure 5

Groups of 8 mice were s.c. immunized with the adjuvanted E7 vaccine and 5 days later ivag instilled with PBS (white symbols) or CpG (black symbols). Mice were sacrificed three days later, at day 9, and flow cytometry staining and analysis were performed on cells recovered from pools of 2 CV. Dead cells were excluded with the aqua dead kit. The percentage of total CD4 (circle) or CD8 (triangle) T-cells expressing the chemokine receptors CXCR3, CCR5, CCR2 and CCR7 (A) and integrin/selectin ligands: αL, α4, α4β7, L-selectin, PSGL-1, CD43, ESL and PSL (B) among either total CD4 or CD8 T cells, are shown. The horizontal bars represent the mean percentages. Data are representative of results obtained in two independent experiments. Significant differences between ivag PBS and ivag CpG treatments within each T-cell populations as well as between the CD4 and CD8 T cells upon ivag PBS are indicated by * p< 0.05, ** p< 0.01, *** p< 0.001.