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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Mucosal Immunol. 2012 Sep 12;6(2):393–404. doi: 10.1038/mi.2012.83

Figure 7. Effect of T-cell depletion on genital tumor regression.

Figure 7

Twelve days after TC-1 challenge mice were either left untreated (stars), or s.c. immunized with the adjuvanted E7 vaccine. Four days later mice received anti-CD4 (triangles), anti-CD8 (squares) antibodies or left untreated (circles and stars), and treatments were repeated every 6 days. The three vaccinated groups received three doses of CpG that were administrated at days 18, 21 and 24. Tumor growth/regression was followed twice a week by bioluminescence imaging. Percentage of survival in each group upon time is represented. Significant differences following an adjusted Log-rank test are indicated by * p< 0.01.