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. 2013 Jan 3;171(2):147–154. doi: 10.1111/cei.12027

Table 1.

Key citations highlighting overlapping subset-specific functions in the dendritic cell (DC) literature to date

Resident cDCs Migratory DCs


CD8+ CD11b+ CD11b CD103+ CD11b+ CD103 CD11b CD103 mLCs
MHC I presentation ++ ++ ++ ++ ++ ++
Cross-presentation ++ + [1822] ++ + [2325] + [25,26]
Apoptotic cell uptake ++ + [91] ++
MHC II presentation ++ ++ ++ ++ ++ ++
IL-12 production ++ + [12,13]
Th1 induction ++ + [1416] ++ + [92,93]
Th2 induction + [14] ++ + [92] ++ ++
Th17 induction + [94] + [95,96] ++ + [97] + [97] + [49]
iTreg induction ++ + [98,99] ++ + [95]
Tolerance committed + [8]
Humoral immunity ++ ++ ++ ++ ++ ++

For a comprehensive set of DC reviews, see Immunology Reviews, 2010, volume 234(1). Commonly attributed subset functions are denoted with ++. MHC: major histocompatibility complex; IL: interleukin; Th: T helper; iTreg: induced regulatory T cells.