Table 1.
Maternal and fetal plasma uric acid
Time (min) | |||||
---|---|---|---|---|---|
n | 0 | 50 | 120 | ||
Maternal | Control | 5 | 4.3 ± 0.3 | 4.6 ± 0.2 | 5.0 ± 0.3 |
Allopurinol | 6 | 4.5 ± 0.3 | 5.0 ± 0.4 | 4.4 ± 0.3 | |
Allopurinol with NO clamp | 6 | 5.5 ± 0.5 | 6.1 ± 0.5 | 5.5 ± 0.5 | |
Fetal | Control | 5 | 12.1 ± 0.6‡ | 12.1 ± 0.9‡ | 12.0 ± 0.7‡ |
Allopurinol | 6 | 12.2 ± 0.4‡ | 12.4 ± 0.5‡ | 9.6 ± 0.4 *†‡ | |
Allopurinol with NO clamp | 6 | 11.9 ± 0.6‡ | 11.6 ± 0.6‡ | 9.5 ± 0.4*†‡ |
Values represent the mean ± SEM at pre-infusion (0), immediate post-infusion (50) and 70 min after the end of infusion (120). Significant differences (P < 0.05) are: *vs. pre-infusion (0), †vs. control, ‡vs. maternal (two-way RM ANOVA with post hoc Newman–Keuls test).