Table 1.
Degradation of eADO (0.05 μm) by monkey WM, monkey CM and murine colon under control conditions or in the presence of either EHNA (10 μm), NBMPR (10 μm), or EHNA + NBMPR combined
| (–) tissue | (+) tissue, control | (+) tissue, + EHNA | (+) tissue, + NBMPR | (+) tissue, + EHNA + NBMPR | |
|---|---|---|---|---|---|
| Monkey WM | 60.0 ± 5.1 (10) | 59.01 ± 10.9 (4) | 63.51 ± 12.2 (2) | 41.93 ± 9.1 (2) | 57.15 ± 3.5 (2) |
| Monkey CM | 110.6 ± 4.9 (8) | 108.87 ± 4.9 (2) | 102.05 ± 7.4 (2) | 61.79 ± 1.8 (2) | 124.77 ± 5.5 (2) |
| Mouse CD38+/+ | 112.8 ± 13.9 (9) | 104.2 ± 16.5 (7) | — | — | 110.0 ± 34.7 (2) |
Values are fmol (mg tissue)−1. No significant differences in (–) tissue versus (+) tissue, control for all groups (P > 0.05). No significant differences between (+) tissue, control and (+) tissue, + EHNA, or (+) tissue, + NBTI, or (+) tissue, + EHNA + NBTI for all groups (P > 0.05). Number of experiments in parentheses.