Table 2.

Effects of antagonists to neural responses and exogenous ADPR and ADP in colons isolated from wild-type CD38^+/+ mice

	IJP		ADPR		ADP
	% inhibition	P value	% inhibition	P value	% inhibition	P value
Apamin	65 ± 7 (9)	0.000001	90 ± 3 (5)	0.001987	71 ± 6 (4)	0.018600
Suramin	55 ± 6 (5)	0.000915	78 ± 2 (5)	0.000010	—	—
PPADS	65 ± 4 (5)	0.000134	73 ± 4 (5)	0.003722	—	—
MRS2500	93 ± 2 (12)	0.000001	96 ± 2 (6)	0.006596	30 ± 6 (6)	0.064000