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Angiotensin II induces EADs both in young/adult (A) and aged (B) isolated LV myocytes. Effects of ATII (2 μmol/L) in both age groups are shown at two different pacing cycle lengths (PCLs). Both young and aged myocytes manifested EADs and triggered activity with significant differences between the two aged groups (from Bapat et al., 2012).
