Figure 1. LacZ gene expression (blue stained cells) in marmoset lung one week after gene transfer.

Transduction across several lobes occurred in an airway-associated and a patchy-diffuse pattern. (a) Gene expression is apparent in the intact trachea above the carina and adjacent to the upper lobes seen here in the un-dissected lung after X-gal processing. (b) shows an en face gross lobe section with blue stained cell patches distributed around the lobe periphery. (c) In another thick en face section the patchy peri-bronchioar distribution is evident, with the boxed region enlarged for clarity in (d). Scale bars 2.5 mm.