Table 1.

World Health Organization (WHO) 2008: the mature T-cell and natural killer cell neoplasms [Campo et al. 2011].

T-cell prolymphocytic leukemia

T-cell large granular lymphocytic leukemia

Chronic lymphoproliferative disorder of NK-cells*

Aggressive NK cell leukemia

Systemic EBV-positive T-cell lymphoproliferative disease of childhood (associated with chronic active EBV infection)

Hydroa vacciniforme-like lymphoma

Adult T-cell leukemia/lymphoma

Extranodal NK/T-cell lymphoma, nasal type

Enteropathy-associated T-cell lymphoma

Hepatosplenic T-cell lymphoma

Subcutaneous panniculitis-like T-cell lymphoma

Mycosis fungoides

Sézary syndrome

Primary cutaneous CD30-positive T-cell lymphoproliferative disorder

Lymphomatoid papulosis

Primary cutaneous anaplastic large-cell lymphoma

Primary cutaneous aggressive epidermotropic CD8-positive cytotoxic T-cell lymphoma*

Primary cutaneous gamma-delta T-cell lymphoma

Primary cutaneous small/medium CD4-positive T-cell lymphoma*

Peripheral T-cell lymphoma, not otherwise specified

Angioimmunoblastic T-cell lymphoma

Anaplastic large cell lymphoma, ALK-positive

Anaplastic large cell lymphoma, ALK-negative*

ALK, anaplastic lymphoma kinase; EBV, Epstein Barr virus; NK, natural killer.

^*These represent provisional entities or provisional subtypes of other neoplasms.

Diseases shown in italics are newly included in the 2008 WHO classification.