Table 3.

Comorbidity rates between disruptive mood dysregulation disorder and other common psychiatric disorders

	Duke Preschool Anxiety Study
	% Rate of DMDD in		% Rate of dx in		OR	CI	p
Comorbidity	dx	No dx.	DMDD	No DMDD
Depressive	23.0	2.9	12.4	1.4	9.9	4.1–23.7	<0.0001
Anxiety	7.5	1.3	72.9	30.7	6.1	1.9–19.0	0.002
ODD	37.7	1.1	67.7	3.8	52.9	17.1–163.8	<0.0001
Conduct Disorder	9.7	2.8	22.1	7.0	3.8	1.5–9.3	0.004
ADHD	23.5	2.4	30.8	3.4	12.6	4.0–39.6	<0.0001
	Great Smoky Mountains Study
Depressive	15.6	0.8	32.7	2.1	23.5	9.9–56.1	<0.0001
Anxiety	5.5	1.0	9.3	1.8	5.2	1.2–22.9	0.03
ODD	23.3	0.5	57.4	2.2	61.0	27.7–134.4	<0.0001
Conduct Disorder	10.9	0.9	23.1	2.1	11.9	3.4–41.0	<0.0001
ADHD	9.2	1.1	6.3	0.7	7.6	2.9–19.7	<0.0001
	Caring for Children in the Community Study
Depressive	11.8	0.8	35.8	3.2	16.3	6.3–42.1	<0.0001
Anxiety	2.5	1.1	7.7	3.6	2.2	0.6–8.2	0.25
ODD	27.0	0.4	70.6	2.3	103.0	40.1–264.2	<0.0001
Conduct Disorder	5.3	1.0	18.8	4.0	4.4	1.2–15.3	0.02
ADHD	4.3	1.1	9.4	1.8	2.9	0.4–23.3	0.32

DMDD= Disruptive mood dysregulation disorder; ODD = Oppositional defiant disorder; ADHD = Attention-deficit/hyperactivity disorder. Bolded p values are significant at p <0.05.