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. 2013 Feb 1;6(1):10–16. doi: 10.1593/tlo.12334

Table 1.

Concordance of HER2 Status Tested by IHC (PATHWAY HER2/neu 4B5) in Biopsy and Surgical Samples.

Biopsy Samples Surgical Samples NPV (%) PPV (%)

IHC 0 to 1+ IHC 2+ to 3+ Total
IHC 0 to 1+ 60 15 75 80 -
IHC 2+ to 3+ 6 22 28 - 78.6
Total 66 37 103
Concordance rate (%) 90.9 59.5 80%

IHC, IHC staining performed with PATHWAY HER2/neu (4B5); NPV, negative predictive value; PPV, positive predictive value.