FIG 4 .
The competitive defect of CFT073 rpoS during UTI is diminished in mice that lack functional phagocyte oxidase. C57BL/6 mice (n = 16) and age-matched congenic mice lacking phagocyte oxidase [p47phox (−/−)] (n = 16) were infected with a 1:1 ratio of CFT073 rpoS and wild-type strains. Animals were infected and sacrificed at 48 hpi, and bacteria were enumerated as described in the Fig. 2 legend. Lines are drawn at the geometric mean relative competitive index (RCI). Statistical significance was assessed by the Mann-Whitney U test.