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The F. tularensis ΔkdhAB mutant strain is not altered in the biosynthesis of O antigen or lipid A. (A) SDS-PAGE analysis of F. tularensis LVS and ΔkdhAB mutant outer membranes. LPS was visualized by zinc staining. (B) Negative-ion MALDI-TOF analysis of lipid A from LVS and ΔkdhAB bacteria.