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. 2012 Jun 11;30(3):487–494. doi: 10.3892/ijmm.2012.1022

Figure 4.

Figure 4.

(A) Antagonists of TRPC and AA interfer with the cell cycle and the migration of MCF-7 breast cancer cells. (i) 2-APB caused a dose-dependent and selective decrease in the S phase of the MCF-7 cell cycle compared to the vehicle control. (ii) D609 had no effect on the cell cycle parameters measured. (iii) 2-APB caused a significant decrease in the migration of MCF-7 cells. (iv) 2-APB caused a dose-dependent and significant decrease in the invasion of MCF-7 cells. (B) The normalized bar figure shows the effects of different concentrations of AA on cell migration.