Table 3.
Effect of bichalcophenes and sodium azide (NaN3) on Salmonella typhimurium TA1535 viability as assessed by colony formation on plate
| Compound |
Viability at NaN3 and bichalcophene concentrationsa (colonies/plate (% of control))
|
|
|---|---|---|
| 5/10 μM | 10/20 μM | |
| None | 35.0 ± 3.1 (100) | |
| NaN3 (1 μg/plate) | 36.9 ± 4.3 (105) | |
| 1A | 33.3 ± 3.0 (95) | 36.0 ± 1.8 (103) |
| 1B | 53.0 ± 1.9 (151)b | 48.7 ± 4.0 (139) |
| 2A | 36.7 ± 3.2 (105) | 44.3 ± 3.7 (127) |
| 2B | 33.0 ± 2.5 (94) | 37.7 ± 2.7 (108) |
| 3A | 49.3 ± 2.8 (141) | 47.7 ± 3.0 (136) |
| 3B | 30.7 ± 2.7 (88) | 32.7 ± 3.1 (93) |
| 4A | 29.7 ± 2.6 (85) | 34.3 ± 2.9 (98) |
| 4B | 40.0 ± 3.7 (114) | 38.7 ± 3.5 (111) |
| 5A | 42.0 ± 4.0 (120) | 43.7 ± 3.9 (125) |
| 5B | 34.3 ± 3.3 (98) | 30.3 ± 1.7 (87) |
Notes:
a
Concentrations investigated for all compounds were 10 and 20 μM except for compounds 1B and 5B – the concentrations used were 5 and 10 μM;
b
significantly different (P < 0.05) from the number of colonies/plate (mean ± SEM) recorded in the absence of bichalcophenes and NaN3. Assays were performed in triplicates with a 10−7 dilution of an overnight Salmonella typhimurium TA1535.
Abbreviation: SEM, standard error of the mean.