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. 2013 Feb 4;7:73–81. doi: 10.2147/DDDT.S40129

Table 8.

Effects of bichalcophenes on sodium azide (NaN3) mutant frequency

Compound# Mutant frequency and (% of NaN3)b
Pre-exposure
Co-exposure
5/10 μM 10/20 μM 5/10 μM 10/20 μM
NaN3 10.43 (100)
1A 1.41 (14)a 1.34 (13)a 1.79 (17)a 0.79 (8)a
1B 1.07 (10)a 1.27 (12)a 0.66 (6)a 0.56 (5)a
2A 1.44 (14)a 1.60 (15)a 1.07 (10)a 1.07 (10)a
2B 1.32 (13)a 1.35 (13)a 1.91 (18)a 0.51 (5)a
3A 0.97 (9)a 1.09 (10)a 1.93 (18)a 0.89 (9)a
3B 1.21 (12)a 1.03 (10)a 0.87 (8)a 0.53 (5)a
4A 6.27 (60)a 3.00 (29)a 1.09 (10)a 1.16 (11)a
4B 0.88 (8)a 0.90 (9)a 2.01 (19)a 1.89 (18)a
5A 1.46 (14)a 2.24 (21)a 1.12 (11)a 0.74 (7)a
5B 1.04 (10)a 1.22 (12)a 0.62 (6)a 0.50 (5)a

Notes:

#

Concentrations investigated for all compounds were 10 and 20 μM except for compounds 1B and 5B – the concentrations used were 5 and 10 μM;

a

significant (P < 0.05) reduction from mutant frequency seen with NaN3;

b

calculated from mutant colonies (Table 6)/viable colonies (Table 3).