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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Prostaglandins Leukot Essent Fatty Acids. 2012 Oct 27;87(6):205–208. doi: 10.1016/j.plefa.2012.09.007

Figure 1. N-3 fatty acids diminish the clustering of murine B cell cholera-toxin induced lipid microdomains.

Figure 1

(A) Samples images demonstrating cross-linked GM1 lipid microdomains on the surface of splenic B220+ B cells isolated from mice fed differing diets. Domains were visualized with cholera toxin subunit B-FITC. The percentage of total kcal from EPA and DHA are indicated. (B) The size of the clusters increases with increasing levels of EPA and DHA. The cluster sizes are normalized to the control since the data are pooled from separate studies [21, 23]. It is important to note that although microdomain size increases on a micron scale, it remains unclear what the impact of the diet is on a nanometer scale.