Table 3.
Analysis of HIV-1 WT and mutant virions by TEM.
| Virus | No. of Particles |
Particle size (nm) |
No. of particles whose cores are: | ||
|---|---|---|---|---|---|
| Cone-Shaped | Centric | Acentric | |||
| WT | 252 | 126 ± 13a | 115 (46)b | 93 (27) | 44 (17) |
| Y145A | 126 | 152 ± 28 | 0 | 51 (40) | 75 (60) |
| S146A | 388 | 134 ± 12 | 156 (40) | 137 (35) | 95 (25) |
| P147L | 138 | 136 ± 25 | 33 (24) | 58 (42) | 47 (34) |
| T148A | 234 | 131 ± 14 | 103 (44) | 74 (32) | 57 (24) |
| S149A | 250 | 141 ± 21 | 65 (26) | 101 (40) | 84 (34) |
| I150A | 108 | 146 ± 19 | 0 | 42 (39) | 66 (61) |
| L151A | 170 | 146 ± 22 | 0 | 92 (55) | 78 (45) |
a
Numbers to the right of "+/−" represent the standard deviation.
b
Numbers in parentheses are percentages of the total number of particles.