Table 1.
Demographic and clinical profile of the inflammatory bowel disease patients and healthy controls
| |
UC |
CD |
IBD |
Healthy controls |
P value |
|---|---|---|---|---|---|
| n = 189(%) | n = 37(%) | n = 226(%) | n = 290(%) | ||
| Mean age ± SD (yr) |
40.81 ± 15.00 |
38.78 ± 14.14 |
40.66 ± 14.90 |
38.08 ± 14.63 |
0.888 |
| Male/Female |
109/80 |
23/14 |
132/94 |
170/120 |
0.961 |
| Smoking |
45 (23.81%) |
9 (24.32%) |
54 (23.89%) |
101 (34.83%) |
0.007* |
| Drinking |
75 (39.68%) |
12 (32.43%) |
87 (38.50%) |
133 (45.86%) |
0.093 |
| Diet composition |
|
|
|
|
|
| vegetarian food |
18 (9.52%) |
6 (16.22%) |
24 (10.62%) |
19 (6.55%) |
0.097 |
| mixed food |
171 (90.48%) |
31 (83.78%) |
202 (89.38%) |
271 (93.45%) |
|
| General state |
|
|
|
|
|
| fever |
32 (16.93%) |
4 (10.81%) |
36 (15.93%) |
|
|
| hemoglobin (g/L) |
114.10 ± 23.98 |
121.22 ± 25.34 |
115.71 ± 24.37 |
|
|
| albumin (g/L) |
39.97 ± 5.88 |
38.12 ± 6.44 |
39.94 ± 6.04 |
|
|
| Disease extent |
|
|
|
|
|
| distal colitis |
140 (74.07%) |
|
|
|
|
| pancolitis |
49 (25.93%) |
|
|
|
|
| ileal |
|
8 (21.62%) |
|
|
|
| colonic |
|
14 (37.84%) |
|
|
|
| ileocolonic |
|
15 (44.11%) |
|
|
|
| Disease severity |
|
|
|
|
|
| mild/moderate |
168 |
30 |
|
|
|
| severe |
21 (11.1%) |
7 (18.92%) |
|
|
|
| Treatment |
|
|
|
|
|
| ASA/SASP |
149 (78.84%) |
20 (54.05%) |
169 (74.78%) |
|
|
| corticosteroids |
47 (24.87%) |
8 (21.62%) |
55 (24.34%) |
|
|
| immunodepressant | 5 (2.65%) | 2 (5.41%) | 7 (3.10%) |
CMV, cytomegalovirus; UC, ulcerative colitis; CD, Crohn’s disease; ASA, aminosalicylic acid; SASP, salicylazosulfapyridine.
*indicate significant difference.