Table 5.
Univariate analysis of risk factors for CMV IgM positive in patients with inflammatory bowel disease
| |
CMV IgM+/IgM- |
|||||
|---|---|---|---|---|---|---|
| |
UC |
CD |
||||
| (3/186) | (1/36) | |||||
| Age |
Number |
P value |
OR (95% CI) |
Number |
P value |
OR (95% CI) |
| ≤50 ys |
2/137 |
1.000 |
0.715 (0.063 ~ 8.065) |
1/23 |
1.000 |
N/A |
| >50 ys |
1/49 |
|
|
0/13 |
|
|
| Sex |
|
|
|
|
|
|
| male |
2/107 |
1.000 |
1.477 (0.132 ~ 16.573) |
1/22 |
1.000 |
N/A |
| female |
1/79 |
|
|
0/14 |
|
|
| Smoking |
|
|
|
|
|
|
| yes |
1/44 |
1.000 |
1.614 (0.143 ~ 18.222) |
1/8 |
0.243 |
N/A |
| no |
2/142 |
|
|
0/28 |
|
|
| Drinking |
|
|
|
|
|
|
| yes |
1/74 |
1.000 |
0.757 (0.067 ~ 8.496) |
0/12 |
1.000 |
N/A |
| no |
2/112 |
|
|
1/24 |
|
|
| Diet composition |
|
|
|
|
|
|
| vegetarian food |
0/18 |
1.000 |
N/A |
0/6 |
1.000 |
N/A |
| mixed food |
3/168 |
|
|
1/30 |
|
|
| Fever |
|
|
|
|
|
|
| yes |
1/31 |
1.000 |
2.500 (0.220 ~ 28.432) |
0/4 |
1.000 |
N/A |
| no |
2/155 |
|
|
1/32 |
|
|
| Hemoglobin (G/L) |
|
|
|
|
|
|
| ≤70 |
1/8 |
0.329 |
11.125 (0.911 ~ 135.909) |
0/0 |
- |
N/A |
| >70 |
2/178 |
|
|
1/36 |
|
|
| Albumin (G/L) |
|
|
|
|
|
|
| ≤35 |
2/19 |
0.031* |
17.579 (1.522 ~ 203.083) |
1/12 |
0.351 |
N/A |
| >35 |
1/167 |
|
|
0/24 |
|
|
| Disease severity |
|
|
|
|
|
|
| mild and moderate |
1/167 |
0.031* |
0.057 (0.005 ~ 0.657) |
1/29 |
1.000 |
N/A |
| severe |
2/19 |
|
|
0/7 |
|
|
| Location |
|
|
|
|
|
|
| distal colitis |
1/139 |
0.337 |
0.169 (0.015 ~ 1.907) |
|
|
|
| pancolitis |
2/47 |
|
|
|
|
|
| ileal |
|
|
|
1/7 |
0.155 |
N/A |
| Colonic |
|
|
|
0/14 |
|
|
| ileocolon |
|
|
|
0/15 |
|
|
| Treatment |
|
|
|
|
|
|
| ASA/SASP |
3/146 |
1.000 |
N/A |
1/19 |
1.000 |
N/A |
| corticosteroids |
3/44 |
0.015* |
N/A |
0/8 |
1.000 |
N/A |
| immunosuppressant | 3/2 | <0.001* | N/A | 0/2 | 1.000 | N/A |
CMV, cytomegalovirus; UC, ulcerative colitis; CD, Crohn’s disease; OR, Odds ratio; CI, confidence interval; ASA, aminosalicylic acid; SASP, salicylazosulfapyridine.
*indicate significant difference.