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. 2012 Nov 8;6:138. doi: 10.1186/1752-0509-6-138

Figure 1.

Figure 1

General scheme of the processes included in the model of ER-dependent gene expression. (A) Reactions of ER dimerisation and binding with two types of ligands - natural hormone (H) and an inhibitor (I); (B) Binding of dimeric forms of receptor-ligand complexes with ERE; (C) Synthesis and degradation of mRNA (r) and protein (p). The detailed description of the scheme is given in the text.