Table 3.
Response according to genotyping of vascular endothelial growth factor
| Genotype | Polymorphism | ORR | % | P* |
|---|---|---|---|---|
| −2578C/A |
CC |
41/116 |
35.3 |
0.798 |
| |
CA |
20/63 |
31.7 |
|
| |
AA |
3/11 |
27.3 |
|
| −2489C/T |
CC |
41/116 |
35.3 |
0.812 |
| |
CT |
19/160 |
31.7 |
|
| |
TT |
4/14 |
28.6 |
|
| −1498 T/C |
TT |
41/116 |
30.8 |
0.832 |
| |
TC |
19/61 |
31.1 |
|
| |
CC |
4/13 |
35.3 |
|
| −634 G/C |
GG |
12/54 |
22.2 |
0.034 |
| |
GC |
30/93 |
32.3 |
|
| |
CC |
22/43 |
51.1 |
|
| +936C/T |
CC |
46/135 |
34.1 |
0.852 |
| |
CT |
14/45 |
31.1 |
|
| |
TT |
4/10 |
40.0 |
|
| +1612 G/A |
GG |
50/139 |
36.0 |
0.333 |
| |
GA |
12/47 |
25.5 |
|
| AA | 2/4 | 50.0 |
*by Fisher’s exact and chi-square test.
ORR: overall response rate.