Table 5.

Multivariate analysis

	Time to progression
Variable	HR	95% CI	p value*
Age	1.521	1.105–2.093	0.010
Gender	1.313	0.939–1.837	0.111
Performance	2.079	0.743–5.816	0.163
Operation	1.143	0.763–1.713	0.516
Stage	0.941	0.763–1.161	0.571
Lauren type	1.035	0.857–1.250	0.720
Number of metastasis	1.375	1.129–1.674	0.002
−634 G/C polymorphism	1.497	1.074–2.088	0.017

*by cox regression test.

VEGF: vascular endothelial growth factor.