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. 2013 Feb 15;8(2):e56619. doi: 10.1371/journal.pone.0056619

Table 4. Percentages and Chi-Square Statistic of Serotonin System Genotypes according to CU Group.

Gene SNP Low CU (N = 92) High CU (N = 41) χ2
Minor Homozygote Heterozygote Major Homozygote Minor Homozygote Heterozygote Major Homozygote (N = 133)
HTR1A rs6295 26 54 20 34 39 27 2.49
HTR1B rs13212041 46 54 43 57 0.11
rs6296 11 31 58 5 49 46 4.08
rs130058 11 37 52 5 56 39 4.57
rs11568817 22 37 41 7 68 24 11.63* #
HTR2A rs6314 29 71 7 93 7.88* #
rs6311 20 45 35 20 34 46 1.54
HTR3B rs1176744 15 39 46 18 37 45 0.18
TPH1 rs1800532 12 38 50 20 44 37 2.49
rs211105 6 47 47 10 37 53 1.18
TPH2 rs4570625 40 60 40 60 0.00
rs11178997 10 90 15 85 0.72
rs7305115 21 42 37 15 56 29 2.17
rs4565946 19 52 29 13 52 35 0.64
SLC6A4 rs2066713 25 35 40 22 46 32 1.64

Note:

*

represents p<0.01 (2-tailed),

#

represents p<0.05 after FDR adjustment for 15 comparisons. SNPs located on the same chromosome are listed in order of their position along the gene.