Table 3. Association of MicroRNA SNPs with OSCC Risk.

Genotype	Cases (n = 325)		Controls (n = 335)		P *	Adjusted OR (95% CI)†
	No.	%	No.	%		Overall OSCC	SCCOP	SCC of Oral Cavity
miR146 rs2910164					0.299
GG (Ref.)	184	56.6	203	60.6		1.0	1.0	1.0
CG+CC	141	43.4	132	39.4		1.3 (0.9–1.8)	1.9 (1.3–3.0)	1.0 (0.6–1.4)
miR149 rs2292832					0.947
CC (Ref.)	158	48.6	162	48.4		1.0	1.0	1.0
CT+TT	167	51.4	173	51.6		0.9 (0.7–1.3)	1.0 (0.7–1.5)	0.9 (0.6–1.3)
miR196 rs11614913					0.871
CC (Ref.)	95	29.2	96	28.7		1.0	1.0	1.0
CT+TT	230	70.8	239	71.3		1.0 (0.7–1.4)	1.0 (0.7–1.6)	1.0 (0.6–1.5)
miR499 rs3746444					0.060
TT (Ref.)	184	56.6	214	63.9		1.0	1.0	1.0
CT+CC	141	43.4	121	36.1		1.3 (0.9–1.9)	1.6 (1.0–2.4)	1.1 (0.8–1.7)

^*Genotype distributions for miR146 rs2910164, miR149 rs2292832, miR196 rs11614913, and miR499 rs3746444 between patients and controls.

^†ORs were adjusted for age, sex, smoking, alcohol drinking, and HPV16 serology.