Table 3. Cox proportional hazards models for RV measures and time to dyspnea.
| HR* | 95%CI | P value | |
| Right ventricle end-diastolic mass | |||
| Unadjusted model | 1.15 | 1.06–1.24 | <0.001 |
| Adjusted model† | |||
| Men | 1.22 | 1.07–1.40 | 0.003 |
| Women | 0.95 | 0.83–1.09 | 0.49 |
| Adjusted model + LV end-diastolic mass | |||
| Men | 1.33 | 1.15–1.54 | <0.001 |
| Women | 1.02 | 0.88–1.17 | 0.82 |
| Right ventricle end-diastolic volume | |||
| Unadjusted model | 1.12 | 1.06–1.18 | <0.001 |
| Adjusted model† | |||
| Men | 1.20 | 1.09–1.32 | <0.001 |
| Women | 0.95 | 0.86–1.06 | 0.37 |
| Adjusted model + LV end-diastolic volume | |||
| Men | 1.25 | 1.10–1.41 | <0.001 |
| Women | 0.99 | 0.87–1.13 | 0.90 |
| Right ventricle ejection fraction | |||
| Unadjusted model | 0.96 | 0.90–1.02 | 0.17 |
| Adjusted model† | 1.03 | 0.96–1.11 | 0.37 |
| Adjusted model + LV ejection fraction | 1.03 | 0.95–1.11 | 0.49 |
| Right ventricle end-systolic volume | |||
| Unadjusted model | 1.24 | 1.10–1.40 | <0.001 |
| Adjusted model† | |||
| Men | 1.24 | 1.02–1.51 | 0.03 |
| Women | 0.85 | 0.67–1.07 | 0.16 |
| Adjusted model + LV end-systolic volume | |||
| Men | 1.27 | 1.03–1.58 | 0.03 |
| Women | 0.87 | 0.68–1.11 | 0.25 |
| Right ventricle stroke volume | |||
| Unadjusted model | 1.16 | 1.07–1.26 | <0.001 |
| Adjusted model† | |||
| Men | 1.30 | 1.14–1.49 | <0.001 |
| Women | 0.96 | 0.83–1.11 | 0.56 |
*
All hazard ratios correspond to ∼1 SD decrement in the respective RV measure (4 g for mass, 20 cc for volumes, 6% in RVEF).
†
Adjusted model includes: age, race/ethnicity, education, body mass index, waist size, hip size, smoking status, diastolic blood pressure, hypertension, creatinine, and IL-6.