Table 4. Simple correlation and multiple stepwise linear regression analysis of risk factors associated with cIMT.
Simple | Stepwise† | Stepwise‡ | Stepwise§ | |||||
r | p-value | β | p-value | β | p-value | β | p-value | |
FVC (% pred) | −0.15 | <0.0001 | −0.03 | 0.02 | − | − | − | − |
FEV1 (% pred) | −0.14 | <0.0001 | − | − | −0.07 | <0.0001 | − | − |
FEV1/FVC ratio | −0.15 | <0.0001 | − | − | − | − | −0.08 | <0.0001 |
Age (years) | 0.45 | <0.0001 | 0.36 | <0.0001 | 0.36 | <0.0001 | 0.35 | <0.0001 |
Gender (male = 1, female = 0) | −0.24 | <0.0001 | −0.20 | <0.0001 | −0.19 | <0.0001 | −0.21 | <0.0001 |
Current smoker (yes = 1, no = 0) | 0.13 | <0.0001 | 0.05 | <0.0001 | 0.05 | <0.0001 | 0.06 | <0.0001 |
BMI (kg/m2) | 0.13 | <0.0001 | 0.07 | <0.0001 | 0.07 | <0.0001 | 0.08 | <0.0001 |
SBP (mmHg) | 0.26 | <0.0001 | 0.14 | <0.0001 | 0.14 | <0.0001 | 0.15 | <0.0001 |
DBP (mmHg) | 0.03 | 0.005 | −0.09 | <0.0001 | −00.1 | <0.0001 | −0.09 | <0.0001 |
TG (mmol/L)* | 0.054 | <0.0001 | −0.03 | 0.156 | −0.03 | 0.17 | −0.02 | 0.57 |
TC (mmol/L) | 0.10 | <0.0001 | 0.001 | 0.980 | 0.000 | 1.00 | 0.002 | 0.94 |
LDL-c (mmol/L) | 0.09 | <0.0001 | 0.12 | <.0001 | 0.12 | <0.0001 | 0.114 | <0.0001 |
HDL-c (mmol/L) | −0.053 | <0.0001 | −0.03 | 0.05 | −0.03 | 0.05 | −0.03 | 0.05 |
HOMA-IR* | 0.07 | <0.0001 | 0.02 | 0.08 | 0.02 | 0.10 | 0.003 | 0.05 |
r, correlation coefficient; β, regression coefficient; SE, standard error. *: log-transfer. †: FVC (% pred) involved. ‡: FEV1 (% pred).
: FEV1/FVC ratio involved.