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. 2013 Feb 15;8(2):e56260. doi: 10.1371/journal.pone.0056260

Table 3. Offspring genotype frequencies in crosses between mice heterozygous for the Pappa2 disruption (−/− = homozygous for Pappa2 disruption, +/− = heterozygous, +/+ = homozygous for wild-type Pappa2).

Stage −/− −/+ +/+ P-valuea
E12.5 3 5 6 0.30
Birth 14 37 11 0.27
Weaningb 24 53 18 0.36
a

Chi-square test of null hypothesis that genotypes are in 1∶2:1 ratio.

b

The sample measured at weaning and into adulthood includes 50 females and 45 males.