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. Author manuscript; available in PMC: 2014 Mar 15.
Published in final edited form as: Stat Med. 2012 Sep 4;32(6):899–913. doi: 10.1002/sim.5597

Table 3.

Group sequential analyses of the cumulative incidence of renal toxicity at quarterly calendar times.

Month 6 9 12 15 18 21 24 27 30 33
Estimate 0.119 0.123 0.097 0.112 0.107 0.088 0.097 0.096 0.090 0.084
SE 0.068 0.041 0.031 0.029 0.025 0.021 0.020 0.019 0.017 0.016
Max Inf 2916 2836 3494 3075 3203 3806 3495 3527 3742 3978
IF 0.074 0.207 0.299 0.376 0.485 0.592 0.707 0.817 0.911 1.000