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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Bioorg Med Chem. 2013 Jan 9;21(5):1123–1135. doi: 10.1016/j.bmc.2012.12.043

Figure 5.

Figure 5

Determination of anti-proliferative effects exerted on cultures of HASMCs by secondary amines. Changes in HASMC proliferation were evaluated using an MTT viability assay, after a 96 h incubation period with a given secondary amine (in cDMSO). Absorbance measurements of each well (570 nm) provided data points, which were expressed as a percentage of the positive control (100%), in which cells were grown in the absence of any test agents. In addition, cDMSO acted as the vehicle to deliver amines; therefore a negative control of 1% cDMSO was also tested for HASMC proliferation inhibition. (*) Indicates a statistically significant difference (p < 0.05) between the given compound/concentration combination and the vehicle alone. The graphical data represents the mean ± SE of triplicate determinations on the extent of HASMC proliferation inhibition in the presence of a) A6–A10 and b) B6–B10.