Skip to main content
. 2012 Sep 21;27(2):253–264. doi: 10.1038/eye.2012.175

Table 2. Lesions simulating retinoblastoma (pseudoretinoblastoma) in 604 patients based on age at presentation.

Pseudoretinoblastoma diagnosis Patient age Number (% per diagnosis) [% per age group]
  Mean, median [range] in years 0–1 year n=283 >1–2 years n=57 >2–5 years n=89 >5 years n=175 All ages n=604
Coats disease 6, 4 [0.2–30] 58 (24) [20] 33 (14) [59] 54 (22) [50] 99 (41) [58] 244 (100) [40]
Persistent fetal vasculature (PFV) 2, 1 [0.2–24] 138 (87) [49] 6 (4) [11] 6 (4) [7] 8 (5) [5] 158 (100) [26]
Vitreous haemorrhage 1, 1 [0.5–8] 21 (78) [7] 3 (11) [5] 1 (4) [1] 2 (7) [1] 27 (100) [5]
Toxocariasis 8, 8 [1–18] 1 (5) [<1] 0 (0) [0] 7 (32) [8] 14 (64) [8] 22 (100) [4]
Familial exudative vitreoretinopathy (FEVR) 7, 7 [0.6–16] 5 (28) [2] 1 (6) [2] 1 (6) [1] 11 (61) [6] 18 (100) [3]
Rhegmatogenous retinal detachment 5, 1 [0.5–24] 10 (56) [4] 0 (0) [0] 3 (17) [3] 5 (28) [3] 18 (100) [3]
Coloboma 3, 1 [0.3–11] 9 (53) [3] 1 (6) [2] 3 (18) [3] 4 (24) [2] 17 (100) [3]
Astrocytic hamartoma 8, 6 [0.5–28] 3 (20) [1] 1 (7) [2] 3 (20) [3] 8 (53) [5] 15 (100) [2]
Combined hamartoma 4, 2 [0.5–16] 4 (27) [1] 5 (33) [9] 1 (7) [1] 5 (33) [3] 15 (100) [2]
Endogenous endophthalmitis 5, 5 [0.2–11] 2 (20) [<1] 0 (0) [0] 2 (20) [2] 6 (60) [3] 10 (100) [2]
Myelinated nerve fibres 4, 4 [0.5–11] 3 (33) [1] 0 (0) [0] 2 (22) [2] 4 (44) [2] 9 (100) [1]
Congenital cataract 3, 1 [0.2–12] 5 (63) [2] 1 (13) [2] 0 (0) [0] 2 (25) [1] 8 (100) [1]
Peripheral uveoretinitis 3, 2 [0.5–6] 3 (43) [1] 1 (14) [2] 0 (0) [0] 3 (43) [2] 7 (100) [1]
Retinopathy of prematurity 2, 2 [0.8–7] 3 (43) [1] 2 (29) [4] 1 (14) [1] 1 (14) [<1] 7 (100) [1]
Non-rhegmatogenous retinal detachment 1, 1 [0.6–4] 4 (80) [1] 0 (0) [0] 1 (20) [1] 0 (0) [0] 5 (100) [<1]
Medulloepithelioma 4, 4 [2–5] 0 (0) [0] 1 (25) [2] 3 (75) [3] 0 (0) [0] 4 (100) [<1]
X-linked retinoschisis 2, 1 [0.6–7] 3 (75) [1] 0 (0) [0] 0 (0) [0] 1 (25) [<1] 4 (100) [<1]
Vitreoretinal tuft 3, 1 [0.6–8] 2 (67) [<1] 0 (0) [0] 0 (0) [0] 1 (33) [<1] 3 (100) [<1]
Incontinentia pigmenti 4, 4 [2–6] 0 (0) [0] 1 (50) [2] 0 (0) [0] 1 (50) [<1] 2 (100) [<1]
Juvenile xanthogranuloma 1, 1 [0.7–0.8] 2 (100) [<1] 0 (0) [0] 0 (0) [0] 0 (0) [0] 2 (100) [<1]
Norrie's disease 1, 1 [0.7–0.8] 2 (100) [<1] 0 (0) [0] 0 (0) [0] 0 (0) [0] 2 (100) [<1]
Vasoproliferative tumour 10, 10 [3–17] 2 (100) [<1] 0 (0) [0] 0 (0) [0] 0 (0) [0] 2 (100) [<1]
Choroidal osteoma 3 0 (0) [0] 0 (0) [0] 1 (100) [1] 0 (0) [0] 1 (100) [<1]
Morning glory disc anomaly 1 1 (100) [<1] 0 (0) [0] 0 (0) [0] 0 (0) [0] 1 (100) [<1]
Retinal capillary hemangioma 16 1 (100) [<1] 0 (0) [0] 0 (0) [0] 0 (0) [0] 1 (100) [<1]
Retrolental fibrosis 2 0 (0) [0] 1 (100) [2] 0 (0) [0] 0 (0) [0] 1 (100) [<1]
Toxoplasmosis 1 1 (100) [<1] 0 (0) [0] 0 (0) [0] 0 (0) [0] 1 (100) [<1]