Table 2. Chromosomal aberrations of EMZL at different extranodal sites.
Location | Chromosomal alteration | Frequency (%) |
---|---|---|
Ocular adnexa | t(11;18)(q21;q21) | 10 |
t(14;18)(q32;q21) | 19 | |
t(3;14)(p14.1;q32) | 14 | |
A20 inactivation (6q23 deletion) | 20 | |
Trisomy 3, 18 | ? | |
5q (ODZ2) and 9p (JMJD2C) | ? | |
Stomach | t(11;18)(q21;q21) | 22–24 |
t(1;14)(p22;q32) | 3 | |
Trisomy 3, 7, 12, 18 | ||
Skin | t(14;18)(q32;q21) | 14 |
t(3;14)(p14.1;q32 | 10 | |
Trisomy 3, 18 | ||
5q (ODZ2) | ||
Intestine | t(11;18)(q21;q21) | 13 |
t(1;14)(p22;q32) | 10 | |
Trisomy 3, 12, 18 | ||
Lung | t(14;18)(q32;q21) | 38–53 |
t(1;14)(p22;q32) | 11 | |
Trisomy 3, 12, 18 | 7 | |
Salivary gland | t(11;18)(q21;q21) | 1 |
t(14;18)(q32;q21) | 5 | |
A20 inactivation | ? | |
Trisomy 3, 7, 18 | ||
Thyroid gland | t(3;14)(p14.1;q32) | 50 |
A20 inactivation | ? | |
Trisomy 3, 12 | ||
Breast | Trisomy 3, 18 | Rare |