Table 2.
Tissue-specific expression correlates to specific transgene integration ePet-eGFP-A1 on rat chromosome 7 in 3 examined animals
| Parameter | Pup analysis |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
| Serotonergic-specific expression | ND | ND | + | + | ND | + | ND | ND | ND | ND |
| Insert ID and position | ||||||||||
| ePet-eGFP-A1; Chr. 7: ∼123.8 Mbp | + | − | + | + | + | + | + | + | − | − |
| ePet-eGFP-A2; Chr. X: ∼85.4 Mbp | − | − | − | − | + | − | − | − | − | − |
| ePet-eGFP-A3; Chr. 2: ∼92.2 Mbp | + | − | − | + | − | − | − | + | + | + |
See Fig. 5. Pup 7 was backcrossed to establish a breeding line for integration ePet-eGFP-A1. ND, not determined.