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. 2013 Mar;27(3):955–964. doi: 10.1096/fj.12-213330

Figure 6.

Figure 6.

aP2-Cre mediated knockout of Grp78 alters glucose homeostasis and adipokine secretion. Blood parameters of 78f/f (n=5–9) and c78f/f mice (n=4–11) at postnatal d 16 to 26. A) Feeding glucose level of 78f/f and c78f/f mice. B) Insulin level. C) C-peptide 2 level. D) Glucagon level. E) Triglyceride level. F) Leptin and adiponectin levels, both of which are hormones secreted by adipose tissue. Normalization of leptin to the WAT volume showed minimal difference between the two genotypes. G) Resistin, TNF-α, monocyte chemotactic protein-1 (MCP-1), and glucagon-like peptide-1 (GLP-1) levels. Data are presented as means ± se. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.