Table 1.

Characteristics of the model and experimental groups

	Control	Trauma	Hemorrhage	Trauma + hemorrhage	TH mAb 1761	TH mAb 1591	TH mAb 1609
Weight, g	25.1 ± 1.1	24.7 ± 1.7	23.7 ± 1.7	24.2 ± 2.8	25.3 ± 1.6	24.9 ± 1.2	24.8 ± 1.3
Hemorrhage, %ETBV	0	0	40.5 ± 1.8	37.0 ± 3.5	34.2 ± 5.1	35.1 ± 2.5	30.8 ± 3.7
Crystalloid, %ETBV	4.0 ± 0.9	6.1 ± 1.7	6.0 ± 1.5	6.2 ± 1.9	7.9 ± 2.2	8.0 ± 1.3	7.0 ± 1.8
Surgery time, min	26 ± 7	32 ± 3	23 ± 5	33 ± 10	39 ± 6	36 ± 7	35 ± 4
Hgb: end-shock, g/dL	13.1 ± 0.6	13.5 ± 0.7	9.1 ± 0.5	10.1 ± 1.0	9.2 ± 1.3	10.1 ± 0.9	10.9 ± 1.5
Lactate: end-shock, mM	4.6 ± 0.7	6.5 ± 0.8	10.7 ± 3.6	10.7 ± 2.1	9.7 ± 1.8	10.4 ± 3.3	13.2 ± 4.6

Groups treated as described in the “Materials and Methods” section. Hemorrhage is total blood volume removed over course of 60-min shock period. Crystalloid is total crystalloid volume administered during surgery and shock period. ETBV = weight (g) × 0.077 mL/g. Hemoglobin (Hgb) and lactate values are measured at the end of 60-min shock period.