Table 3.
Material/technique | Characteristics | Medical applications |
---|---|---|
Ligands attached to nanoparticles | Surface modification with functional groups High degree of engineering precision Control the size of the nanoparticles |
Labeling, tracing and imaging Sensing and detection Recognition and attachment to damaged or diseased tissue followed by release of therapeutic compound |
Quantum dots | Emit different wavelengths over abroad range of the light spectrum from visible to infrared, depending on their size and chemical composition Influence the fluorescence properties of the particles |
Fluorescent probes Detection and targeting |
Nanocapsules | Consists of a shell and a space Can be made in specific sizes, shapes, and in reasonable quantities Control the release of substances or protect them from the environment Higher safety and efficacy Evasion of the host immune system and delivery of therapeutic agent to target sites |
Slowly release loading drugs Lipid nanocapsules as nanocarriers e.g. Buckyball-based treatment for AIDS |
Nanoporous materials | Ability of nanopores of certain sizes to let some substances pass and others not, or to force molecules | Nanoporous membranes for molecules like DNA and RNA Can be coupled to sensors or used for drug-delivering implants |
Polymers | Allow for judicious selection for targeting and delivery Can be used to improve the function of the nanoparticle High degree of engineering precision |
Drug carrying devices or implants Combining multi-modal therapy and imaging |
Sorting biomolecules and precise sorting | Nanopores capable of rapid and precise sorting | Gene analysis and sequencing |