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. Author manuscript; available in PMC: 2014 Jun 15.
Published in final edited form as: Adv Drug Deliv Rev. 2012 Nov 2;65(6):822–832. doi: 10.1016/j.addr.2012.10.007

Table 3.

Potential applications for nanotechnologies in drug delivery [69].

Material/technique Characteristics Medical applications
Ligands attached to nanoparticles Surface modification with functional groups
High degree of engineering precision
Control the size of the nanoparticles
Labeling, tracing and imaging
Sensing and detection
Recognition and attachment to damaged or diseased tissue followed by release of therapeutic compound
Quantum dots Emit different wavelengths over abroad range of the light spectrum from visible to infrared, depending on their size and chemical composition
Influence the fluorescence properties of the particles
Fluorescent probes
Detection and targeting
Nanocapsules Consists of a shell and a space
Can be made in specific sizes, shapes, and in reasonable quantities
Control the release of substances or protect them from the environment
Higher safety and efficacy
Evasion of the host immune system and delivery of therapeutic agent to target sites
Slowly release loading drugs
Lipid nanocapsules as nanocarriers e.g. Buckyball-based treatment for AIDS
Nanoporous materials Ability of nanopores of certain sizes to let some substances pass and others not, or to force molecules Nanoporous membranes for molecules like DNA and RNA
Can be coupled to sensors or used for drug-delivering implants
Polymers Allow for judicious selection for targeting and delivery
Can be used to improve the function of the nanoparticle
High degree of engineering precision
Drug carrying devices or implants
Combining multi-modal therapy and imaging
Sorting biomolecules and precise sorting Nanopores capable of rapid and precise sorting Gene analysis and sequencing