Table 5.
Relative expression of ANXA1 and LGALS1 mRNA in chronic gastritis (CG) and gastric adenocarcinoma (GA) groups according to gender, infection by H. pylori, and presence of cagA+ genotype.
| Variable | AN XA1 | LG AL S1 | ||
|---|---|---|---|---|
| CG | GA | CG | GA | |
| Gender | ||||
| Female | 22 (55%) | 6 (30%) | 22 (55%) | 6 (30%) |
| (mean ± SD) | 4.40 ± 1.80 | 6.67 ± 2.00 | 0.29 ± 3.55 | 4.81 ± 3.26 |
| Male | 28 (45%) | 14 (70%) | 28 (45%) | 14 (70%) |
| (mean ± SD) | 4.08 ± 2.32 | 3.25 ± 5.16 | 0.60 ± 2.61 | 1.66 ± 2.96 |
| P | 0.63 | 0.04* | 0.75 | 0.10 |
| H. pylori | ||||
| Positive | 16 (40%) | 11 (55%) | 16 (40%) | 11 (55%) |
| (mean ± SD) | 4.04 ± 2.59 | 3.91 ± 5.48 | −0.05 ± 3.97 | 3.33 ± 3.16 |
| Negative | 24 (60%) | 9 (45%) | 24 (60%) | 9 (45%) |
| (mean ± SD) | 4.40 ± 1.60 | 4.35 ± 4.05 | 0.75 ± 2.46 | 1.36 ± 3.23 |
| P | 0.47 | 0.61 | 0.24 | 0.73 |
| Genotype cagA | ||||
| Positive | 10 (62.5%) | 3 (27.3%) | 10 (62.5%) | 3 (27.3%) |
| (mean ± SD) | 2.91 ± 2.74 | 6.40 ± 3.00 | −1.57 ± 3.62 | 2.58 ± 1.26 |
| Negative | 6 (37.5%) | 8 (72.7%) | 6 (37.5) | 8 (72.7%) |
| (mean ± SD) | 5.49 ± 1.56 | 2.77 ± 6.52 | 1.89 ± 3.74 | 2.80 ± 3.10 |
| P | 0.14 | <0.01* | 0.09 | 0.51 |
*Significant difference.