Table 4.
Brain regions identified by univariate fMRI analyses in patients and controls
| Region | BA | Cluster size | Peak voxel |
|||
|---|---|---|---|---|---|---|
| x | y | z | z score | |||
| Patients, NP-silence, p < 0.001 | ||||||
| RSTG, MTG, IFG | 22, 21, 44 | 56.2 | 51 | −12 | −3 | 6.57 |
| R occipital | 18, 19, 37 | 9.2 | 36 | −87 | −6 | 5.57 |
| L + R SMA | 6, 24, 32 | 21.5 | 9 | 12 | 39 | 5.54 |
| L STG, MTG | 22, 21 | 37.9 | −42 | −33 | 12 | 5.40 |
| L occipital | 19, 18, 37 | 11.6 | −39 | −90 | 0 | 4.79 |
| R precentral gyrus, MFG | 6, 4, 3 | 5.9 | 54 | 0 | 45 | 4.47 |
| L precentral gyrus | 6 | 1.6 | −48 | 3 | 39 | 4.36 |
| L cerebellum | 1.5 | −12 | −60 | −15 | 4.24 | |
| Controls, NP-silence, p < 0.001 | ||||||
| R STG, MTG, IFG, precentral | 22, 21, 38, 44, 45, 47, 4, 6 | 79.3 | 51 | −21 | −6 | > 8.00 |
| L STG, MTG, IFG, precentral, occipital, fusiform | 22, 21, 38, 44, 45, 47, 6, 4–1, 18, 19, 37 | 162.7 | −63 | −24 | 9 | 6.95 |
| R occipital, fusiform, cerebellum | 19, 37, 18 | 26.7 | 45 | −75 | −9 | 5.58 |
| Controls > patients, NP-silence, p < 0.001 | ||||||
| L STG | 22 | 4.2 | −51 | −18 | 9 | 4.14 |
| Controls > patients, NP-silence, p < 0.01 | ||||||
| L STG, MTG | 22, 21 | 19.8 | −57 | −42 | 6 | 4.40 |
Cluster size in cubic centimeters. Peak voxel coordinates (x, y, z) in Montreal Neurological Institute space (in mm). BA, Brodmann area; SMA, supplementary motor area; MFG, middle frontal gyrus. Note: for controls > patients, NP-silence, the cluster at p < 0.01 includes a peak voxel that was not present at p < 0.001 since at the higher threshold this voxel was part of a separate cluster that failed to meet cluster size threshold.