Fig. 1.

C16/C4 HAD activity ratio and LCKAT activity of patients and controls. C16/C4 HAD activity ratio and LCKAT activity have been analyzed in fibroblasts of 40 patients with HADHA and/or HADHB mutations and 215 controls as described in “Materials and Methods” section. Patients can be divided into three groups: LCHAD (filled circle), LCKAT (open square) and MTP (open triangle) deficiency. Mean C16/C4 HAD activity ratio of control group 0.72 ± 0.14 (mean ± SD; vertical error bars). Mean LCKAT activity of control group 18.3 ± 5.4 nmol/(min.mg protein) (mean ± SD; horizontal error bars)