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. Author manuscript; available in PMC: 2013 Feb 18.
Published in final edited form as: Acta Neuropathol. 2011 Sep 30;122(6):737–745. doi: 10.1007/s00401-011-0880-5

Table 1.

Case demographics

Disease
Control
AD CBD FTLD-TDP LBD MSA PSP PiD
Number (n) 10 6 9 19 7 9 6 7
Sex (M:F) 2:8 2:4 7:2 13:6 4:3 6:3 3:3 2:5
Age, mean (SD) 81.4 (8.7) 66.7 (9.6) 65.0 (11.9) 77.8 (7.8) 68.7 (5.9) 73.7 (7.4) 65.5 (8.2) 78.0 (9.4)
Brain weight, mean (SD) Braak stage 1,055 (140) 1,093 (90) 1,117 (166) 1,293 (178) 1,363 (188) 1,205 (106) 1,046 (194) 1,261 (107)
 0 - 4 3 5 2 3 3 1
 I–II - 2 5 8 4 6 3 5
 III–IV 1 - 1 6 1 - - 1
 V–VI 9 - - - - - - -
 Median V–VI 0 I–II I–II I–II I–II I–II I–II
Ventricular enlargement
 None 1 1 - 9 4 1 - 3
 Mild 3 - 3 6 2 5 - 3
 Mod 2 3 2 4 1 3 3 1
 Severe 4 2 4 - - - 3 -
 Median Mod Mod Mod Mild None Mild Mod Mild
Atherosclerosis
 None 1 3 3 4 3 2 5 4
 Mild 6 3 3 4 1 5 1 1
 Mod 3 - 3 8 2 1 - 2
 Severe 0 - - 3 1 1 - -
 Median Mild Mild Mild Mod Mild Mild None None
Brain atrophy
 None 2 - - 13 3 1 - 4
 Mild 1 2 2 2 2 5 - 3
 Mod 3 2 2 4 1 3 1 -
 Severe 4 2 5 - 1 - 5 -
 Median Mod Mod Severe None Mild Mild Severe None

SD standard deviation, M:F male:female, Mod moderate, AD Alzheimer’s disease, LBD Lewy body disease, FTLD-TDP frontotemporal dementia-Tar DNA binding protein 43, MSA multiple system atrophy, PiD Pick’s disease, CBD corticobasal degeneration, PSP progressive supranuclear palsy