Table 1.
Disease
|
Control | |||||||
---|---|---|---|---|---|---|---|---|
AD | CBD | FTLD-TDP | LBD | MSA | PSP | PiD | ||
Number (n) | 10 | 6 | 9 | 19 | 7 | 9 | 6 | 7 |
Sex (M:F) | 2:8 | 2:4 | 7:2 | 13:6 | 4:3 | 6:3 | 3:3 | 2:5 |
Age, mean (SD) | 81.4 (8.7) | 66.7 (9.6) | 65.0 (11.9) | 77.8 (7.8) | 68.7 (5.9) | 73.7 (7.4) | 65.5 (8.2) | 78.0 (9.4) |
Brain weight, mean (SD) Braak stage | 1,055 (140) | 1,093 (90) | 1,117 (166) | 1,293 (178) | 1,363 (188) | 1,205 (106) | 1,046 (194) | 1,261 (107) |
0 | - | 4 | 3 | 5 | 2 | 3 | 3 | 1 |
I–II | - | 2 | 5 | 8 | 4 | 6 | 3 | 5 |
III–IV | 1 | - | 1 | 6 | 1 | - | - | 1 |
V–VI | 9 | - | - | - | - | - | - | - |
Median | V–VI | 0 | I–II | I–II | I–II | I–II | I–II | I–II |
Ventricular enlargement | ||||||||
None | 1 | 1 | - | 9 | 4 | 1 | - | 3 |
Mild | 3 | - | 3 | 6 | 2 | 5 | - | 3 |
Mod | 2 | 3 | 2 | 4 | 1 | 3 | 3 | 1 |
Severe | 4 | 2 | 4 | - | - | - | 3 | - |
Median | Mod | Mod | Mod | Mild | None | Mild | Mod | Mild |
Atherosclerosis | ||||||||
None | 1 | 3 | 3 | 4 | 3 | 2 | 5 | 4 |
Mild | 6 | 3 | 3 | 4 | 1 | 5 | 1 | 1 |
Mod | 3 | - | 3 | 8 | 2 | 1 | - | 2 |
Severe | 0 | - | - | 3 | 1 | 1 | - | - |
Median | Mild | Mild | Mild | Mod | Mild | Mild | None | None |
Brain atrophy | ||||||||
None | 2 | - | - | 13 | 3 | 1 | - | 4 |
Mild | 1 | 2 | 2 | 2 | 2 | 5 | - | 3 |
Mod | 3 | 2 | 2 | 4 | 1 | 3 | 1 | - |
Severe | 4 | 2 | 5 | - | 1 | - | 5 | - |
Median | Mod | Mod | Severe | None | Mild | Mild | Severe | None |
SD standard deviation, M:F male:female, Mod moderate, AD Alzheimer’s disease, LBD Lewy body disease, FTLD-TDP frontotemporal dementia-Tar DNA binding protein 43, MSA multiple system atrophy, PiD Pick’s disease, CBD corticobasal degeneration, PSP progressive supranuclear palsy