The protein composition of the Prp19 complex in human and yeast S. cervisiae. The first four yeast proteins are the homologues of the first four human proteins. The last five components in the yeast column are written in the order of discovery. Only the 8 characterized components of the NineTeen complex have been listed, although a number of additional currently uncharacterized components have also been co-purified with this complex in yeast [94, 122, 123].