Table 4.
(A) Genes found to be modulated subsequent to in utero B(a)P exposure in rat offspring. Expression fold changes of genes in “regulation of blood pressure” gene ontology biological process (GO:008217) are shown as well as the REFSEQ-mRNA accession number; (B) genes found not to be modulated subsequent to in utero B(a)P exposure in rat offspring.
| REFSEQ-mRNA | Fold Change | Gene Symbol | Gene Name |
|---|---|---|---|
| A | |||
| NM_004797 | 8.9 | Adipoq | Adiponectin, C1Q and collagen domain |
| NM_000029.3 | 8.5 | AngII | Angiotensinogen (serpin peptidase inhibitor clade A, member 8) |
| NM_000025 | 9.3 | Adrb3 | Adrenergic, beta-3-, receptor |
| NM_001058.3 | 9.9 | Tacr1 | Tachykinin receptor 1 |
| NM_138712 | 5.8 | PPARγ | Peroxisome proliferator-activated receptor |
| NM_001057 | −2.2 | Tac2 | Tachykinin 2 |
| Gene symbol | Gene name | ||
|
| |||
| B | |||
| ADAMTS18 | ADAM metallopeptidase with thrombospondin type 1 motif 18 | ||
| AGTR2 | Angiotensin II receptor, type 2 | ||
| GPD1 | Glycerol-3-phosphate dehydrogenase 1 (soluble) | ||
| HRASLS5 | HRAS-like suppressor family, member 5 | ||
| Tac4 | Tachykinin receptor 4 | ||
| Tacr2 | Tachykinin receptor 2 | ||
| Tacr3 | Tachykinin receptor 3 | ||
| TF | Transferrin | ||
| TFF2 | Trefoil factor 2 | ||
| THRSP | Thyroid hormone responsive protein, isoform CRA_a | ||
Gene ontology biological process analysis of gene expression from control P 53 versus 1200 μg/kg BW transcriptome data set. Column 1 – REFSEQ mRNA number. Column 2 – Fold change. Column 3 – Gene symbol. Column 4 – Gene name.