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. 2012 Sep 4;42(2):234–239. doi: 10.1093/ageing/afs122

Table 2.

Linear regression models predicting leucocyte telomere length

Univariate
Multivariate
Model 1
Model 2
Model 3
Model 4
Model 5
Coefficient (95% CI) P-value Coefficient (95% CI) P-value Coefficient (95% CI) P-value Coefficient (95% CI) P-value Coefficient (95% CI) P-value Coefficient (95% CI) P-value
Sociodemographics
 Female 0.041 (−0.066 to 0.141) 0.479 −0.005 (−0.10 to 0.100) 0.938 −0.006 (−0.113 to 0.102) 0.920 −0.021 (−0.124 to 0.088) 0.735 0.000 (−0.105 to 0.105) 0.996 −0.019 (−0.128 to 0.094) 0.769
 Age (year) −0.047 (−0.026 to 0.011) 0.422 −0.058 (−0.027 to 0.009) 0.320 −0.062 (−0.028 to 0.008) 0.296 −0.065 (−0.028 to 0.008) 0.269 −0.060 (−0.027 to 0.008) 0.302 −0.067 (−0.029 to 0.008) 0.266
 Illiterate 0.022 (−0.082 to 0.121) 0.707 −0.005 (−0.104 to 0.096) 0.939 −0.007 (−0.107 to 0.095) 0.908 −0.034 (−0.134 to 0.077) 0.596 −0.017 (−0.116 to 0.088) 0.617 −0.046 (−0.149 to 0.071) 0.485
 Married 0.135 (0.022 to 0.261) 0.020 0.114 (−0.001 to 0.231) 0.052 0.108 (−0.009 to 0.227) 0.071 0.108 (−0.008 to 0.226) 0.068 0.123 (0.008 to 0.242) 0.036 0.111 (−0.008 to 0.234) 0.067
 Lower incomea −0.086 (−0.202 to 0.028) 0.139 −0.139 (−0.236 to −0.023) 0.018 −0.129 (−0.230 to −0.012) 0.029 −0.145 (−0.238 to −0.024) 0.014 −0.141 (−0.239 to −0.024) 0.017 −0.141 (−0.244 to −0.020) 0.021
Diseases
 Diabetes 0.055 (−0.082 to 0.232) 0.348 0.049 (−0.093 to 0.228) 0.406 0.023 (−0.134 to 0.197) 0.711
 Hypertension −0.038 (−0.163 to 0.082) 0.517 −0.025 (−0.151 to 0.099) 0.680 −0.029 (−0.157 to 0.095) 0.632
 Cardiovascular diseases 0.033 (−0.085 to 0.154) 0.571 0.024 (−0.098 to 0.149) 0.678 0.003 (−0.127 to 0.133) 0.964
 Cerebrovascular disease −0.010 (−0.252 to 0.211) 0.863 −0.013 (−0.258 to 0.207) 0.830 −0.020 (−0.288 to 0.207) 0.746
 Parkinson's disease −0.070 (−2.157 to 0.518) 0.229 −0.060 (−2.207 to 0.637) 0.305 −0.055 (−1.989 to 0.707) 0.350
Mental state
 Depressive symptomsb 0.086 (−0.001 to 0.009) 0.137 0.140 (−0.004 to 0.015) 0.235 0.127 (−0.004 to 0.015) 0.289
 Minor mental symptomsc 0.062 (−0.009 to 0.030) 0.289 −0.057 (−0.045 to 0.026) 0.612 −0.035 (−0.043 to 0.031) 0.760
 Cognitive impairmentd 0.027 (−0.162 to 0.263) 0.643 −0.027 (−0.245 to 0.153) 0.648 −0.028 (−0.252 to 0.159) 0.655
Neighbourhood experiencee
 Social support 0.025 (−0.008 to 0.013) 0.668 0.133 (−0.001 to 0.025) 0.080 0.115 (−0.004 to 0.024) 0.149
 Perceived security −0.063 (−0.033 to 0.010) 0.278 −0.117 (−0.049 to 0.006) 0.118 −0.117 (−0.051 to 0.007) 0.131
 Adequacy of facilities −0.049 (−0.039 to 0.015) 0.400 −0.050 (−0.044 to 0.022) 0.506 −0.043 (−0.044 to 0.024) 0.572

Multivariate regression models were generated sequentially with sociodemographic factors only (Model 1), sociodemographics plus disease factors (Model 2), sociodemographics plus mental state factors (Model 3), sociodemographics plus neighbourhood experience factors (Model 4) and sociodemographics plus all factors Model 5), respectively.

aMonthly income <1,000 USD.

bTaiwanese depression questionnaire score.

cChinese health questionnaire score.

dShort portable mental status questionnaire score and criteria.

eNeighbourhood quality index subscales.