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. 2013 Feb 13;6:93–102. doi: 10.2147/DMSO.S40840

Figure 4.

Figure 4

Synergistic effects of metformin and resveratrol-HMB on insulin tolerance test in mice.

Notes: Effects of standard dose, low-dose, and very low-dose metformin compared with low-dose metformin-resveratrol-CaHMB and with very low-dose metformin-resveratrol-CaHMB on 30-minute plasma glucose response to insulin (0.75 U/kg body weight) in db/db mice. Data are expressed as the mean ± standard error of the mean (n = 10). Bars with the same letter superscripts are not significantly different from each other; bars with nonmatching letter superscripts indicate significant differences between groups (P < 0.02).

Abbreviations: HMB, hydroxymethylbutyrate; Met, metformin; RESV, resveratrol.