Figure 11.

Visualization of geometrical preferences of the insulin molecule in complexation with (A) PLA-PEG1₄, (B) PLA-PEG2₂, and (C) PLA-PEG4₁ after molecular simulations in vacuum.

Notes: The peptide molecules are rendered in tube (elements color coded) and thin-ribbon secondary structures (violet). Color codes for insulin tube rendering: C (cyan), O (red), H (white), and P (yellow). The respective Connolly molecular electrostatic potential surfaces for the nanoparticulate matrix in transparent display mode are also shown.