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. Author manuscript; available in PMC: 2013 Feb 18.
Published in final edited form as: Vision Res. 2009 Aug 22;50(7):652–664. doi: 10.1016/j.visres.2009.08.018

Table 1.

RT-qPCR analysis showing acute induction of Nrf2 responsive anti-oxidant genes (NQO-1 and GCLM) by the RPE of Nrf2+/+ mice (n = 4 each group) after 1 and 21 day exposure to cigarette smoke. Expression was normalized to β-actin.

Mouse Day NQO-1
GCLM
Fold changea p-value Fold changea p-value
Nrf2+/+ 1 3 0.11 3.1 0.0003
21 2.9 0.04 1.7 0.04
Nrf2−/− 1 1.4 0.19 1.6 0.17
21 1.6 0.27 0.42 0.48
a

Ratio of CS/air.