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. Author manuscript; available in PMC: 2014 Feb 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2012 Dec 27;267(1):49–56. doi: 10.1016/j.taap.2012.12.013

Figure 9. Proposed mechanistic model.

Figure 9

VCD exposure inhibits PI3K signaling, leading to increased GSTM protein, resulting in increased GSTM:ASK1 protein interaction.