Figure 1.

Trend of different rating and clinical parameters at weeks 6 and 36 between the two groups.Note: While the figure fails to show any substantial differences between groups, this highlights the fact that the effect of agomelatine add-on therapy was substantially maintained within week 6 and week 36, independent of the ongoing mood stabilizer treatment.Abbreviations: BMI, body mass index; CGI-BP-I/S, Clinical Global Impression/Severity scales for Bipolar Disorder; HAM-D-17, Hamilton Depression Rating-Scale 17-item; PSQI, Pittsburgh Sleep Quality Index; YMRS, Young Mania Rating Scales.