Table 1.
Galantamine switch
|
Donepezil increase
|
Additional memantine
|
||
---|---|---|---|---|
16 mg (n = 16) | 24 mg (n = 16) | total, 10 mg/day (n = 15) | 20 mg/day (n = 15) | |
Age (years), mean (SD) | 75.4 (8.8) | 78.8 (9.2) | 76.8 (6.2) | 74.4 (4.8) |
Sex, n (%) | ||||
Male | 10 (63) | 8 (50) | 9 (60) | 8 (53) |
Female | 6 (38) | 8 (50) | 6 (40) | 7 (47) |
MMSE, mean (SE) | 17.1 (4.1) | 16.1 (5.4) | 11.8 (3.1) | 11.1 (3.9) |
Disease duration (months), mean (SD) | 26.3 (14.1) | 28.2 (18.7) | 41.2 (19.4) | 45.3 (17.6) |
Abbreviations: MMSE, Mini Mental Status Examination; SD, standard deviation; SE, standard error of the mean.